Bharatstudent.com
Sign Up | Login
Networking Videos
Restoring memory function in Alzheimer's disease may now be possible
New Delhi, Jan 24 (ANI): A study now finds that a new approach to Alzheimer's disease (AD) may eventually make it possible to reverse memory loss, a hallmark of the disease in its later stages. The study was published in the journal Brain. The research, led by University at Buffalo, scientists found that by focusing on gene changes caused by influences other than DNA sequences -- called epigenetics -- it was possible to reverse memory decline in an animal model of AD. Speaking about it, senior author Zhen Yan said: "In this paper, we have not only identified the epigenetic factors that contribute to the memory loss, we also found ways to temporarily reverse them in an animal model of AD". The research was conducted on mouse models carrying gene mutations for familial AD -- where more than one member of a family has the disease -- and on post-mortem brain tissues from AD patients. Yan further added, "We found that in Alzheimer's disease, many subunits of glutamate receptors in the frontal cortex are down regulated, disrupting the excitatory signals, which impairs working memory." The researchers found that the loss of glutamate receptors is the result of an epigenetic process known as repressive histone modification, which is elevated in AD. They saw this both in the animal models they studied and in post-mortem tissue of AD patients.
 
Latest Videos

Manhunt underway in Lyon ...

Igarashi and Gilmore win ...

U.S. President Donald ...

Quake rattles Tokyo ahead ...

Iraq's racy TV in ...

'Your time is ...

France's Le Pen ...

Mexico's new jaguar ...

Wenger says his football ...

Congress got saved from ...

Countrymen believed in PM ...

Wenger says his football ...

Jayme Closs kidnapper ...

Novartis gets approval ...

Trade frustrations grow ...

Week ahead on Wall Street
 

News


Manhunt underway in Lyon ...

U.S. President Donald ...

Quake rattles Tokyo ahead ...

Iraq's racy TV in ...

Technology


Mexico's new jaguar ...

Banksy does it again in Venice

Prague Zoo puts ...

In western France, ...

 
Bharatstudent
About
News
Mobile
RSS Feeds
FAQ
Contact Us
Advertise with Us
Networking
Friends
Gangs
Photos
Videos
Classifieds
Study Zone
Study India
Study Abroad
Notifications
Exam Results
My First Job
Cafe Bharat
Hindi
Tamil
Telugu
Kannada
Malayalam
GenX Zone
Game Zone
Live Radio
Greetings
Recharge Mobiles
Cricket
Become a FAN on Facebook
© All rights reserved to BharatStudent.com Terms of Use | Privacy